SANTA CLARA -- Tight end Vernon Davis hasn't practiced all week but sounds encouraged his left hamstring won't keep him out of Sunday's game against Indianapolis.

He is listed as questionable, as are defensive tackle Ray McDonald (ankles), safety Eric Reid (concussion) and running back LaMichael James (knee).

Davis said he was simply waiting on clearance from team doctors to play. He's played in the 49ers' past 98 games, including playoffs. On Friday, he did individual conditioning drills on a side field as practice got under way.

  • Reid should be cleared Saturday if post-concussion symptoms don't surface, as has been the case since he got hurt making a tackle in Sunday's second quarter at Seattle. The rookie told Comcast SportsNet Bay Area that he passed Friday's contact test.

  • McDonald vowed to play despite injuries to both ankles. Coach Jim Harbaugh said McDonald could be a game-time decision. McDonald has missed only two games since 2008.

  • Aldon Smith is listed as probable with a back injury, which has limited the linebacker in practice all week. He wasn't injured in Friday's accident that resulted in his arrest for suspicion of drunken driving and marijuana possession.

  • Quarterback Colin Kaepernick (foot), linebacker NaVorro Bowman (wrist) and guard Mike Iupati (shoulder) also are listed as probable.

  • The Colts have ruled out safety LaRon Landry (ankle). Joe Lefeged likely will start in place of Landry alongside Antonie Bethea (toe), who's listed as questionable.

  • Starting linebacker Pat Angerer (knee) is doubtful, while the Colts list four wideouts as probable: Darrius Heyward-Bey (ribs), T.Y. Hilton (groin), David Reed (quadriceps) and Reggie Wayne (shoulder).

  • Both the 49ers and Colts are coming off Sunday losses, and neither side has ever lost two straight games under their current coaching regimes. The 49ers are 8-0 in regular-season rebound games under Harbaugh, following their seven losses and one tie since 2011. Last season, the Colts went 5-0 after losses in Chuck Pagano's first season, though he was present for just the first two rebound games before undergoing leukemia treatment. Since 2011, only the 49ers, Green Bay and Atlanta haven't lost back-to-back games.

  • Kaepernick is 5-0 as a starter at Candlestick Park. In those starts, he was 94 of 144 for 1,379 yards with nine touchdowns, one interception and a 114.3 passer rating. He also ran for 271 yards and three TDs.

  • The 49ers' Anquan Boldin had five catches for 145 yards and a touchdown in the Baltimore Ravens' win over the Colts in last season's wild-card playoff game.

  • The 49ers' run defense ranks 25th in the league (117.5 yards per game), and the Colts run offense is fifth (130 ypg.).

  • Jim Nantz and Phil Simms will call Sunday's game as CBS's top broadcast team.