SANTA CLARA -- The 49ers went a lackluster 2-2 in the season's proverbial "first quarter." Still to come are 12 games, only three of which are against teams currently with a winning record.

Those upper-echelon foes are the Tennessee Titans (3-1; host 49ers on Oct. 20), the New Orleans Saints (3-0; host 49ers on Nov. 17) and the Seattle Seahawks (4-0; visit 49ers on Dec. 8).

All other opponents have one or no wins, except for the Arizona Cardinals (2-2) and Houston Texans (2-2).

Here is a glimpse at the remaining regular-season schedule:

  • Oct. 6, vs. Houston: The Texans blew a 20-3 lead at home Sunday against the Seahawks, who maintained a two-game lead on the 49ers in the NFC West. Matt Schaub has thrown a pick-6 in three straight games. Linebacker Brian Cushing must pass post-concussion test to be cleared for Sunday night's game at Candlestick.

    ST LOUIS, MO - SEPTEMBER 26:   Colin Kaepernick #7 looks to pass in the first quarter against the St. Louis Rams at Edward Jones Dome on September 26, 2013
    ST LOUIS, MO - SEPTEMBER 26: Colin Kaepernick #7 looks to pass in the first quarter against the St. Louis Rams at Edward Jones Dome on September 26, 2013 in St Louis, Missouri. (Photo by Dilip Vishwanat/Getty Images) (Dilip Vishwanat)

  • Oct. 13, vs. Arizona: Sunday's win at vulnerable Tampa Bay leveled out the Cardinals' record, as they've played only one home game thus far.

  • Oct. 20, at Tennessee: The Titans might not have starting quarterback Jake Locker, who sustained a hip injury in Sunday's win over the New York Jets that could sideline him a month, according to The Tennesseean's Jim Wyatt.

  • Oct. 27, at Jacksonville (in London): The 49ers should be heavy favorites in Wembley Stadium when they play the back end of their two-game road trip, and do so against likely the NFL's worst team.

  • Nov. 3: Bye.

  • Nov. 10, vs. Carolina: Idle last weekend, the Panthers are hoping their Sept. 22 win over the New York Giants still offers enough momentum to carry them to their first winning season since 2008.

  • Nov. 17, at New Orleans: A return trip to the Superdome will spark memories of last season's Super Bowl defeat, and those thoughts must be blocked out against a Saints team that looks fully charged (excuse the blackout-related pun) upon coach Sean Payton's return.

  • Nov. 25, at Washington: Sunday's win in Oakland marked the first this season by the-Washington-football-team-whose-nickname-is-becoming-more-ignored-in-mainstream-media.

  • Dec. 1, vs. St. Louis: The Rams looked abysmal in Thursday night's 35-11 loss to the 49ers. How much further will Jeff Fisher's club fall over the next two months?

  • Dec. 8, vs. Seattle: The 49ers' bid for a third straight NFC West title could come down to the Seahawks' visit at Candlestick.

  • Dec. 15, at Tampa Bay: The Buccaneers' turmoil is already in full swing after quarterback Josh Freeman got benched this past weekend in favor of rookie Mike Glennon, who failed to end their winless start.

  • Dec. 23, vs. Atlanta: Tony Gonzalez and Julio Jones put forth phenomenal efforts Sunday night, but the Falcons fell to 1-3 in their loss to New England. The Falcons' visit to San Francisco will mark the 49ers' final regular-season appearance at Candlestick Park. With two losses already, the 49ers might not be playing any playoff games there, either.

  • Dec. 29, at Arizona: Will Carson Palmer (10 sacks so far) survive all season and start this finale?

    For more on the 49ers, see Cam Inman's Hot Read blog at blogs.mercurynews.com/49ers. Follow him on Twitter at twitter.com/CamInman.