No. 1 Louisville vs. No. 8 Colorado State (CBS, 2:15 p.m.): Colorado State dispatched Missouri with ease -- it was the only victory in a nightmarish Thursday for the Mountain West -- and will be well-prepared for Louisville's pressure. (CSU coach Larry Eustachy is a top-notch strategist.) But the Rams don't have enough of everything to withstand the force of nature that is the tournament's No. 1 overall seed. Pick: Louisville.
No. 4 Saint Louis vs. No. 12 Oregon (TBS, 4:10 p.m.): This has the makings of a thriller. Both teams are more than the sum of their parts, and both are happy to grind away in a halfcourt duel. Oregon point guard Dominic Artis appears to be returning to his pre-injury form (13 points, four steals vs. Oklahoma State). He'll need to be strong with the ball and savvy with his decisions against Saint Louis' rugged defense. Pick: Oregon.
No. 6 Memphis vs. No. 3 Michigan State (CBS, 11:45 a.m.): Memphis survived a bevy of last-minute mistakes to outlast Saint Mary's. It won't be so fortunate Saturday: Michigan State has the athleticism to match the Tigers, in addition to being bigger, tougher and better coached. Plus, it's essentially a home game for the Spartans in Auburn Hills. Pick: Michigan State.
No. 1 Gonzaga vs. No. 9 Wichita State (TNT, 5:40 p.m.): If you're just returning from a trip to the outer reaches of the solar
No. 6 Arizona vs. No. 14 Harvard (TNT, 3:10 p.m.): The Crimson pulled off Thursday's biggest upset, dispatching No. 3 seed New Mexico and busting brackets across the country. Harvard will be facing a deep and talented opponent that has far more scoring options than New Mexico. Harvard is a nice story and easy to root for. But it's hard to see the Crimson matching Mark Lyons, Solomon Hill and Nick Johnson basket-for-basket for 40 minutes. Pick: Arizona.
No. 4 Michigan vs. No. 5 Virginia Commonwealth (CBS, 9:15 a.m.): If you can only watch one game Saturday, this should be it: The mighty Wolverines, with Glenn Robinson III, Tim Hardaway Jr. and player of the year candidate Trey Burke against scrappy, upstart VCU. But there's a reason Michigan is only a two-point favorite: VCU isn't really a scrappy upstart, and Shaka Smart has as much March mojo as any coach in the tournament. Buckle up. Pick: Michigan (in the game of the day).
No. 4 Syracuse vs. No. 12 Cal (TBS, 6:40 p.m.): The Bears sent UNLV packing by combining a brilliant game plan, stellar play from guard Allen Crabbe and steady production from the role players (big man Robert Thurman in particular). They will need all that and more against the Orange, who are bigger and more talented than anyone in the Pac-12 and pose unique problems with their zone defense. The Bears can't rely on jumpers. They must attack, push the tempo and hope for the best. Pick: Syracuse.
No. 3 Marquette vs. No. 6 Butler (CBS, 4:45 p.m.): Marquette dodged elimination with a furious rally and last-second shot to stun Davidson in the second round. Butler won't allow any last-second escapes -- no team is sturdier under pressure than coach Brad Stevens' group. Look for the tournament-tested Bulldogs to suck the life out of Marquette with their smothering defense and timely shooting. Pick: Butler.