Last year, San Bernardino had 29 homicides by the end of November.
Two of the 46 deaths have been ruled acts of self-defense.
"Our numbers are really elevated compared to last year at this time," police Sgt. Gary Robertson said.
The month began with the stabbing death of Martin Luther King Daniels III, 28, of San Bernardino. Police said Daniels and his girlfriend, Brianna Jones, 26, of San Bernardino, had been fighting over relationship issues Nov. 9 when Jones stabbed him.
Daniels died at a hospital three days later.
Prosecutors charged Jones with murder on Nov. 14.
Four days after the fatal stabbing, police found the body of a woman in the 1100 block of East Highland Avenue. An autopsy revealed foul play, but police haven't released any further details about her death.
They admit the case is puzzling because fingerprint and missing person databases have revealed no matches to the unidentified woman.
"We still do not know who she is, and no one reported missing nationwide matches her description," Robertson said. "That is very unique."
Investigators are working on creating a photo of the woman to release this week, with the hopes that someone will recognize her.
The day after investigators found the woman's body, homicide detectives received another case. This time, the victim was a 76-year-old retiree whose body was found in one of the city's upscale neighborhoods.
Mary Elizabeth Blaskey was found dead in her ransacked home in the 3000 block of Fremontia Drive. Her missing Lexus ES300 was found Saturday.
San Bernardino County coroner's officials made some preliminary determinations on the cause of her death, but detectives have not released those details. They have not identified any suspects.
"Every day we're getting new information," Robertson said, "and we're pursuing all the leads as thoroughly as possible, but at this point, we have not been able to focus on a single individual."
The month ended with a pair of killings about four miles from each other.
Leon McLaughlin and his wife had returned home from running errands and getting dinner on Monday evening when an armed robber confronted McLaughlin in the parking lot of his apartment complex.
McLaughlin, 38, was shot when he tried to protect his wife from the robber.
Police say it appears McLaughlin and his wife were random victims.
"We've been recontacting people we've already spoken to and are hoping to have a break in the case," Robertson said.
Later that night, homicide detectives came to a home in the 1200 block of North Mountain View Avenue after the body of a man was found there. Robert Forrest Dearmin Jr., 27, had been stabbed multiple times.
No one else was at the scene when police arrived.
Police said Dearmin had been listed as homeless about a year ago, but it was unknown if he was still homeless at the time of his death.
Investigators say transients often go to that home.
"It was kind of a crash pad for some folks," Robertson said.
Police came to the home about a week before the homicide because neighbors had reported people going into the vacant residence.
Dearmin was not one of the people police found inside the home, and none of the people who were there have been found by police.
"We don't even know if they were present or even involved in this incident in any way," Robertson said.
Anyone with information on homicides may call 909-384-5742 or the anonymous tip line at 909-384-5656.
Reach Melissa via email or call her at 909-386-3878.
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