The Cardinal (13-1, 2-0 Pac-12) extended their conference winning streak to 80 games and improved to 15-0 against the Utes.
Ogwumike entered the game having posted 10 straight double-doubles, but she managed just six rebounds against the Utes.
Iwalani Rodrigues led Utah (9-4, 0-2) with 21 points. Freshman Paige Crozon added 11 points on 4-of-7 shooting.
The Utes were within 37-35 with 14:32 left following a layup by Taryn Wicijowski on a nice feed by Danielle Rodriguez. But Ogwumike sparked a 10-2 Stanford run with a contested jumper. Joslyn Tinkle capped the run with a steal and layup and 47-37 Cardinal lead.