Newport Beach police spokeswoman Kathy Lowe says police received a report at about 2:45 p.m. Monday of six or seven shots fired at the medical office near Hoag Hospital.
Lowe says officers responding found a man dead from multiple gunshot wounds to the upper torso in a patient examination room. They found the suspect in the same room and took him into custody.
Lowe did not know the identity of either man or what their relationship may have been.
She says no one else was injured and it appears to be an isolated incident.
Detectives are interviewing others from the building.