Investors also worried that the Federal Reserve may be close to reducing its economic stimulus.
The Dow fell 93 points, or 0.6 percent, to close at 15,518 points Tuesday.
The Standard & Poor's 500 index fell nine points, or 0.6 percent, to 1,697.
The Nasdaq composite index fell 27 points, or 0.7 percent, to 3,665.
American Eagle slid 12 percent to $17.57 after the teen retailer slashed its earnings forecast, blaming weak sales.
CVS Caremark fell 3 percent to $59.89 after cutting the top end of its 2013 earnings forecast.
Three stocks fell for every one that rose on the New York Stock Exchange. Volume was below average at 3.1 billion shares.