ST. LOUIS -- Trade deadline acquisitions Hunter Pence and Marco Scutaro credited the Giants chemistry with making it easy to get acclimated to a new clubhouse, but you could forgive Pence and Scutaro if they are still a bit perplexed by what they've seen on the field.

The Giants lineup, long known for a lack of production, has turned into a juggernaut away from pitcher-friendly AT&T Park. Pence and Scutaro helped lead the charge Wednesday as the Giants shut out the St. Louis Cardinals 15-0 at Busch Stadium.

It was the franchise's largest shutout win since May 24, 2000, and the most lopsided in over 100 years of facing the Cardinals. With their latest double-digit outburst, the Giants are now the league's leading team in road scoring at 5.18 runs per game.

"It's been incredible to watch," said Pence, who had two early RBI singles. "It's just been good at-bats all the way up and down the lineup."

Said Scutaro, who hit a ninth-inning grand slam to cap a seven-RBI night: "Nights like this are always welcome. You see the lineup we have and I don't see any reason we can't keep doing this."

Manager Bruce Bochy feels the same way, and he said Pence and Scutaro will continue to be part of the answer. Pence has settled in as the No. 5 hitter, and Scutaro was at No. 2 on Wednesday, when he had three hits to raise his average as a Giant to .347.

"We've always thought a lot of Marco," Bochy said. "It's nice to have him on this

Bochy said Scutaro's defensive flexibility means the Giants can use him all over the infield when Pablo Sandoval returns from a hamstring injury. But with the way the Giants are hitting of late, it might be hard to figure out which player to pull on any given day.

The league's second-lowest-scoring team in home games has scored 56 runs while winning five of the first six games on this road trip, and the Giants have done their damage with one big inning after another. The sixth inning Wednesday included five runs and four hits, more hits than Giants starter Ryan Vogelsong gave up in his seven innings.

The Giants tacked on four more runs in the eighth, two on Scutaro's double. Up 11-0 in the ninth, they loaded the bases in front of Scutaro. The under-the-radar acquisition crushed a Mitchell Boggs fastball into the left-field stands, becoming the first Giant since Jeff Kent in 2001 to drive in seven runs in one game.

"You can't give at-bats away," Scutaro said of his ninth-inning approach.

The seven RBIs marked the most by a Giants third baseman in 20 years.

"Both those guys (Scutaro and Pence) are giving us professional at-bats," Vogelsong

Vogelsong was described that way for much of last season, but his 2012 run has bordered on spectacular. Given an early lead, Vogelsong seemed to turn his lauded focus up another notch. He gave up just three hits and got through the sixth inning for the 21st time in his 21 starts.

"I don't pitch to the score," he said. "I pitch like it's 0-0. I've had times in the past where I pitched to the score and it got me in trouble. We had a really good game plan and I was able to execute it."

Vogelsong lowered his ERA to 2.27, the lowest mark in the National League by nearly two-tenths of a run. Among major league starters, Vogelsong trails only Los Angeles Angels ace Jered Weaver (2.13) in ERA.

He got help not only from the offense, but from a defense that made several highlight plays. None was better than shortstop Brandon Crawford's sliding stop and strong throw from deep in the hole that saved a run in the fourth and ended the inning with the Giants holding a 2-0 lead.

"This is up there," Vogelsong said, when asked if the total team effort was the best he has seen. "We swung the bats real well. It felt like I was just along for the ride."