— Nov. 2, 2007: The body of Kercher, 21, is found in her apartment in Perugia, Italy. Investigators say she was killed the night before.
— Nov. 6, 2007: Knox is arrested with then-boyfriend Raffaele Sollecito and Diya "Patrick" Lumumba, the Congolese owner of pub where Knox occasionally worked.
— Nov. 20, 2007: Lumumba, implicated by Knox statements to police, is released from jail for lack of evidence.
— Dec. 6, 2007: Ivory Coast national Rudy Hermann Guede is extradited from Germany and jailed on arrival in Italy.
— Oct. 28, 2008: Judge indicts Knox and Sollecito on murder and sexual assault charges. Guede, who was granted a fast-track trial, is convicted of murder and sexual assault and sentenced to 30 years in prison.
— Jan. 16, 2009: Trial of Knox and Sollecito opens in Perugia.
— June 12, 2009: Knox takes stand; tells court she was shocked by Kercher's death, offers alibi, says police beat her into making false statement.
— Dec. 4, 2009: Court finds Knox guilty of murder and sexual assault, sentences her to 26 years in prison. Sollecito is convicted of same charges and sentenced to 25 years.
— Dec. 22, 2009: Appeals court upholds Guede's conviction but cuts sentence to 16 years.
— Nov. 24, 2010: Appeals trial for Knox and Sollecito opens in Perugia.
— Dec. 16, 2010: Italy's highest criminal court upholds Guede's conviction and 16-year prison sentence.
— June 29, 2011: Independent forensic report ordered by the appeals court finds much of the DNA evidence used to convict Knox and Sollecito is unreliable.
— Oct. 3, 2011: Appeals court clears Knox, Sollecito of murder convictions, orders them freed immediately
— March 26, 2013: Italy's highest criminal court overturns acquittal of Knox and Sollecito, orders new trial.