Newark Police Detective Eugenio Gonzalez says the Dodge Neon struck a tree south of downtown at around 1:30 a.m. Monday. Gonzalez says all 10 people were trapped inside the vehicle after the crash.
Police say the mother and two of her children, ages 1 and 2 years old, are in critical condition.
Police have not released the victims' names.
The cause of the crash is still under investigation.