The powerful explosion rattled buildings on the other side of the capital and sent a pillar of white smoke into the sky over eastern Kabul.
Initial reports were that a car bomb exploded in front of a member of parliament's house in the east of the city, Afghan police officer Jahn Agha said.
Kabul provincial police spokesman Hashmad Stanakzi said the suicide bomber attacked the convoy of "foreign advisers" with a car packed with explosives.
"The explosion was very big. It set the nearby buildings on fire," Stanakzi said.
He said people were killed in the attack but could not estimate how many. Several wounded were rushed to hospitals.