First Duke, then Syracuse. Now second-seeded Villanova has been eliminated.

The Wildcats became the highest seed to fall in the NCAA tournament so far after Shabazz Napier scored 25 points in leading No. 7 seed Connecticut to a 77-65 victory Saturday night in Buffalo, N.Y.

Napier had 21 points in the second half and helped put away the game by hitting three consecutive 3-pointers to put the Huskies ahead 54-45 with 6:08 remaining.

"He led us to victory," said coach Kevin Ollie, who is 2-0 in his tournament debut, two years since taking over after Jim Calhoun stepped down because of health issues, and a year after the Huskies were barred from postseason play because of academic sanctions. "He was just unbelievable in that second half: 21 points, crucial 3s, dagger 3s. He was 30 feet out, and he was making them."

Connecticut (28-8) advanced to an East Regional semifinal Friday against the winner of Sunday's game between No. 3 seed Iowa State and No. 6 seed North Carolina.

Ryan Arcidiacono scored 18 points for Villanova (29-5).

Michigan State 80, Harvard 73: Branden Dawson scored 26 points to help the fourth-seeded Spartans (28-8) withstand a furious rally by the 12th-seeded Crimson (27-5) in Spokane, Wash.

Harvard trailed by 16 early in the second half but took a 62-60 lead when Laurent Rivard hit a 3-pointer with 7:12 remaining. Travis Trice answered with a 3 of his own on the next possession, and Michigan State never trailed again.


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"They stayed poised, and we knew they were going to make a run," said Michigan State guard Gary Harris, who scored 18 points. "They're here for a reason."

The Spartans will play No. 1 seed Virginia or No. 8 seed Memphis on Friday.

Wesley Saunders led Harvard with 22 points.

West Regional

Wisconsin 85, Oregon 77: Ben Brust hit a go-ahead 3-pointer with 1:07 left, and the second-seeded Badgers (28-7) beat the seventh-seeded Ducks (24-10) in Milwaukee.

Trailing by 12 at the half, coach Bo Ryan's veteran squad didn't flinch.

"To be able to handle that smack in the face in the first half and come back and deliver one of our own says a lot about this group," Ryan said.

Frank Kaminsky led the way with 19 points. Brust had 12 -- all on 3-pointers.

Joseph Young led Oregon with 29 points.

Wisconsin will play No. 3 seed Creighton or No. 6 seed Baylor on Thursday.

San Diego State 63, North Dakota State 44: Xavier Thames scored 30 points, and the fourth-seeded Aztecs (31-4) routed the 12th-seeded Bison (26-7) in Spokane, Wash., to reach the Sweet 16 for the second time in school history.

Thames, who was 9 of 19 from the field, had five assists and ended the comeback hopes of the Bison with a six-point spurt late in the second half that pushed the Aztecs' lead to 12.

"That kid had a couple moves where, well, put it this way, we don't have anybody that can simulate it in practice," Bison coach Saul Phillips said.

San Diego State will play No. 1 seed Arizona or No. 8 seed Gonzaga on Thursday.

Midwest Regional

Louisville 66, Saint Louis 51: Luke Hancock scored 21 points, and the fourth-seeded Cardinals (31-5) shrugged off a cold shooting performance to defeat the fifth-seeded Billikens (27-7) in Orlando, Fla.

Louisville shot under 45 percent, had 19 turnovers and got only 11 points from star Russ Smith. It didn't matter, with Saint Louis going 0 for 15 from 3-point range and struggling to take care of the ball.

"Everything's not going to be sweet or pretty," Smith said. "We're just getting the job done."

The Cardinals will play No. 1 seed Wichita State or No. 8 seed Kentucky on Friday.

Michigan 79, Texas 65: Nik Stauskas had 17 points and eight assists to lead the second-seeded Wolverines (27-8) past the seventh-seeded Longhorns (24-11) in Milwaukee.

Stauskas made four of Michigan's 14 3-pointers.

"Huge win for us," coach John Beilein said. "These guys believe, and they did a great job."

Jordan Morgan added 15 points and 10 rebounds to help Michigan advance to a Friday game against No. 14 seed Mercer or No. 11 seed Tennessee.

South Regional

Florida 61, Pittsburgh 45: Scottie Wilbekin scored 21 points, and the top-seeded Gators (34-2) beat the ninth-seeded Panthers (26-10) in Orlando, Fla., to extend their winning streak to 28 games and reach the Sweet 16 for the fourth straight year.

Florida will play No. 4 seed UCLA or No. 12 seed Stephen F. Austin on Thursday.

After a lackluster performance in a first-round win against Albany, the Gators vowed to play with more energy and intensity, and Wilbekin led the way.