The Sharks say Katie Moore died Monday after a nine-month battle with liver cancer.
Dominic Moore missed San Jose's final two playoff games last April to be with his wife shortly after she was diagnosed with a rare form of liver cancer.
Dominic Moore was acquired by San Jose last February in a deal with Tampa Bay. He is currently an unrestricted free agent.
The Sharks offered their condolences to the Moore family and called Katie Moore's courage during the illness an inspiration.