Kirk Cousins will start for the Washington Redskins on Sunday in place of Robert Griffin III.
The team announced Saturday night that the fourth-round pick from Michigan State will make his first career start against the Cleveland Browns.
Griffin, the NFL's leading passer, sprained his right knee in last week's overtime win over the Baltimore Ravens. He was limited in practice all week.
The decision apparently came after Griffin was re-examined by doctors Saturday.
Griffin tweeted: "The decision was not my own. But I will be there for my team!!! In every way I possibly can."
Chiefs: The team put wide receiver Dwayne Bowe on injured reserve, ending his season and potentially his up-and-down career in Kansas City.
The Chiefs' leading receiver already had been ruled out of Sunday's game at Oakland after hurting his ribs while delivering a block in last weekend's game at Cleveland.
Bowe has 59 catches for 801 yards and three of the Chiefs' eight TD grabs this season.
Bowe was playing this season on a $9.5 million deal as the team's franchise player, and it's possible the two sides could agree on a new deal or the Chiefs could franchise him again.
Bowe wasn't happy getting the tag last season, though. He refused to sign his tender until well into training camp.
Jets: Wide receiver Braylon Edwards was listed as questionable after being limited all week with a hamstring issue, but coach Rex Ryan is expecting to see him out there Monday night against the Tennessee Titans in a game the Jets (6-7) must win in order to stay in playoff contention.
Edwards, a former 49er, was claimed off waivers from Seattle on Tuesday, reuniting with the team he helped lead to the AFC title game in 2009 and 2010.
Seahawks: Seattle re-signed wide receiver Deon Butler and placed receiver Charly Martin on injured reserve because of a calf injury.
Butler spent the past three seasons with the Seahawks but played in just five games during the 2011 season while he recovered from a broken leg suffered against the 49ers near the end of the 2010 season.
Ravens: Injured Baltimore linebacker Ray Lewis won't play Sunday against the Denver Broncos. Lewis has been sidelined since tearing his right triceps Oct. 14 against the Dallas Cowboys. The 37-year-old Lewis has been practicing for the past two weeks but obviously is not healthy enough to return.
Saints: New Orleans placed safety Malcolm Jenkins and offensive lineman Charles Brown on injured reserve, ending their seasons.