Wesley Saunders scored 18 points and Laurent Rivard had 17 to help 14th-seeded Harvard pull off Thursday's biggest upset in the NCAA tournament, 68-62 over No. 3 New Mexico in a West Regional game in Salt Lake City.
The Ivy League advanced a team for the first time in the tournament since Cornell made the regional semifinals in 2010. It also was Harvard's first NCAA tournament win.
Harvard will try to keep it going Saturday against sixth-seeded Arizona.
Alex Kirk had 22 points for the Lobos, a popular pick to make the Final Four.
Arizona 81, Belmont 64: Mark Lyons scored 23 points and the sixth-seeded Wildcats rolled past the Bruins in Salt Lake City.
The Wildcats used their huge size advantage to shut down the Bruins, who are 0-6 in tournament games. Arizona held a 44-18 edge on the boards, outscored Belmont 36-18 in the paint, blocked five shots and outshot the Bruins from 3-point range.
"I was more impressed with team I saw tonight than I was scouting them," Belmont coach Rick Byrd said of the Wildcats. "I thought they were more engaged and focused and I think if they play that way, they can beat a lot of people."
Wichita State 73, Pittsburgh 55: Malcolm Armstead scored 22 points, Cleanthony Early added 21 and the ninth-seeded Shockers ousted the Panthers in Salt Lake City.
Pitt's leading scorer, Tray Woodall, missed his first four
"It's a bitter taste in my mouth to end my career with one of worst game I've ever played," said Woodall, who came into the game averaging 11.8 points. "I'm sorry. I let my team down."
Marquette 59, Davidson 58: Vander Blue's layup with one second left capped Marquette's rally from a nine-point deficit and gave the third-seeded Golden Eagles a victory over the Wildcats in Lexington, Ky.
Blue and Jamil Wilson made consecutive 3-pointers to bring Marquette within 58-57 with 11 seconds left. The Golden Eagles then caught a huge break when De'Mon Brooks' long inbounds pass went out of bounds at midcourt with 5.5 seconds left, providing another opportunity.
Blue took Wilson's inbounds pass, drove left and found room for the winning basket. He then sealed Marquette's improbable win by stealing Davidson's last-ditch inbounds pass at midcourt.
"All I was thinking was, 'if I get to the rim, I have to finish,' " Blue said.
Butler 68, Bucknell 56: Andrew Smith had 14 points and 16 rebounds, Roosevelt Jones added 14 points, and the sixth-seeded Bulldogs made their free throws down the stretch to hold off the 11th-seeded Bison.
"I just think they've played in so many big games, they're not the type of team that's going to get rattled," Bucknell coach Dave Paulsen said of Bucknell, which made 18 of 20 free throws in the final 4:43.
Louisville 79, North Carolina A&T 48: Russ Smith scored 23 points and set a Louisville NCAA tournament record with eight steals as the top-seeded Cardinals demolished the Aggies in Lexington.
Michigan State 65, Valparaiso 54: Derrick Nix had 23 points and a career-high 15 rebounds to help power the third-seeded Spartans in Auburn Hills, Mich.
Colorado State 84, Missouri 72: Dorian Green scored 17 of his 26 points in the first half and the eighth-seeded Rams ran away from the No. 9 Tigers in Lexington.
Michigan 71, South Dakota 56: Glenn Robinson III scored 21 points and Mitch McGary added 13 points and nine rebounds, helping the Wolverines beat the Jackrabbits in Auburn Hills.
Virginia Commonwealth 88, Akron 42: Troy Daniels had 23 points as the Rams routed the Zips in Auburn Hills.
It was the most lopsided victory by a fifth-seeded team over a No. 12 in NCAA tournament history. The previous mark was set by Wyoming in a 35-point win over Howard in 1981 and matched by Tennessee against Long Beach State in 2007.