Courtney Walker added 16 points, nine rebounds, and five steals for the Aggies (7-3), who have won their last seven games after opening with losses to three top-10 teams—Louisville, Connecticut and Penn State.
Texas A&M led by eight at the half and pulled away behind Walker, who had 12 of her points after the break.
Haley Texada scored 19 points and Brittany Chambers added 15 to lead Kansas State (7-2).
Chambers only played 28 minutes after spraining her right ankle in the Wildcats' loss to TCU on Sunday. She didn't start, snapping a streak of 101 straight games she had started, but quickly entered the game.
The game was part of a three-day tournament at UNLV.